Abstracts Abstract G404(P) Table 1 Main results significantly lower compared to females. This pattern was consistent across all gestation groups. After adjustment for confounding variables, gestation at birth, duration of ventilation and postnatal steroids remained independent factors that significantly affected z-score at discharge. Conclusion The longitudinal weight profile of preterm infants in Wales is significantly below predicted standards as per the B1990R. While suboptimal nutrition is multifactorial with scope for further improvement, we speculate that the observed growth failure is significantly contributed by an unrealistic expectation of postnatal growth. A large population based longitudinal growth chart may be more representative of appropriate growth in this population. G405(P) TO EVALUATE AND COMPARE THE EFFICACY OF COMBINED SUCROSE AND NON-NUTRITIVE SUCKING FOR ANALGESIA IN NEWBORNS UNDERGOING MINOR PAINFUL PROCEDURE: A RANDOMISED CONTROLLED TRIAL P Thakkar, 2K Arora, 2K Goyal, 3R Das. 1Pediatrics, Baroda Medical College, Baroda, India; 2 Pediatrics, Dayanand Medical College and Hopital, Ludhiana, India; 3Pediatrics, All India Institute of Medical Sciences, Bhubneshwar, India group IV. Group III had significant decrease in the mean PIPP score compared to other groups (p = 0.001). Mean PIPP score also decreased significantly with any intervention as compared to no intervention (p = 0.001). Conclusions Sucrose and NNS in combination are effective in providing analgesia in full term neonates undergoing minor painful procedure, with the combined intervention being more effective than single intervention. G406(P) AN AUDIT OF RESPIRATORY SUPPORT PRACTICE AND OUTCOMES IN THE LESS THAN 27 WEEK GESTATION POPULATION ACROSS THREE TERTIARY NEONATAL CENTRES IN LONDON 1 A Mintoft, 1C Harris, 2R Gandhi, 1L De Rooy, 3N Sim, 3L Tyszczuk, 2M Sellwood. Neonatology, St George’s NHS Trust, London, UK; 2Neonatology, University College Hospitals NHS Trust, London, UK; 3Neonatology, Queen Charlotte’s and Chelsea Hospitals NHS Trust, London, UK 1 10.1136/archdischild-2016-310863.396 1 10.1136/archdischild-2016-310863.395 Aim Neonates frequently undergo minor painful procedures for which they are often not offered any analgesia. Sucrose and Non-nutritive sucking (NNS) can be effective non-pharmacological methods for pain relief in neonates. Aim of the study was to evaluate and compare the efficacy of combined sucrose and nonnutritive sucking for analgesia in newborn infants undergoing minor painful procedure. Methods This randomised control trial (RCT) was conducted in the neonatal intensive care unit of a tertiary care hospital over a period of one year. 180 full term neonates with birth-weight >2200 g and age >24 h were randomised to one of four interventions administered two min before the procedure: 2 ml of 30% sucrose (group I, n = 45) or non-nutritive sucking (NNS) (group II, n = 45) or both (group III, n = 45) or none (group IV, n = 45). Primary outcome was composite score based on Premature Infant Pain Profile (PIPP) score. Results Baseline variables were comparable among the groups. Mean (±SD) PIPP score was 3.42 ± 1.6 in group III, 7.47 ± 1.6 in group I, 8.42 ± 2.5 in group II, and 12.49 ± 2.9 in archdischild 2016;101(Suppl 1):A1–A374 Despite advances in neonatal intensive care, respiratory morbidities for very low birth weight babies have remained the same.1,2 This is associated with high costs, both to infants and families and in financial terms to the NHS.(Phibbs 2006) There is considerable variation in respiratory management of this vulnerable population across neonatal units. The majority of neonatal units in the United Kingdom contribute neonatal data to a common platform ‘Badger.net’. In this study we aim to pilot extraction of respiratory data from Badger.net from three tertiary units in London to examine the applicability and feasibility of auditing and bench marking routinely collected data. Methods Data were collected for all babies <27 weeks gestational age (GA) for 2013 (January-December). The information was collected from Badger.net, the medical notes were checked for missing data. Data were compared using the Mann Whitney U test. Results The median GA and birth weight (BW) were similar in all units. Only inborn babies from Unit A (a surgical centre) were considered (Table 1). There was a significant difference in the invasive ventilation days in units A and B compared to unit C (p = 0.006 and 0.009 respectively) (Fig 1). The percentage of babies with chronic lung disease at 36 weeks GA did not differ (84%, 88% and 82%, units A, B and C respectively). Babies in A237
1/--страниц