вход по аккаунту



код для вставкиСкачать
Hellegren, Department of Dmatology, Gothenhurg, Sweden. Stockholm, Almiquist and Wisksell,
1967. 108 pages, 5%x 8%inches (21.4 x 13.8 cm.).
One illustration. Swedish Kroner 32.00.
The book describes a survey of 39,591 Swedes
for one hundred skin and fifteen rheumatic diseases. The diagnostic criteria are both acceptable
and clearly stated. The survey aimed t o relate
the diseases to the usual epidemiologic variables:
age, sex, marital status, occupation, population
density and climate. Computer techniques
for handling the large volume of data are described.
An interesting aspect of the book is the detailed discussion of individuals who refused to
participate in the survey. Nonrespondents are
usually assumed to be nondiseased. Of 1,142 respondents, 0.53 per cent had definite or classical
rheumatoid arthritis. Of a matched group of nonrespondents who were intensively pursued, 2.5 per
cent had definite or classical rheumatoid arthritis.
Since the nonresponse rate in this survey was
20-25 per cent, and since surveys rarely have
fewer than 15 per cent nonrespondents, this bias
may drastically affect the prevalence estimates of
many population surveys.
Unfortunately, Hellgren presents very little
data. The overall prevalence of skin diseases and
prevalence of skin and rheumatic diseases in the
subsample of respondents and nonrespondents are
given, and detailed figures on xanthelasma of the
eyelids by area, sex and occupation are reported.
Bnt no figures on association of skin and joint
disease appear, nor are overall prevalences of
rheumatic diseases and their associations with
other variables presented.
The survey described in this book must be
compared with the results of contemporary
American surveys on rheumatic diseases. The population studies in Sudbury, Framingham, New
Haven, Tecumseh, Puerto Rico and Indian reservations have produced only brief reports on
prevalence and few papers on specialized subjects.
None have yet presented detailed reports of survey methods and resnlts. Perrot aptly described
these surveys as having “Tons of data untouched
by human thought.” At least Hellgren has carefnlly described his population and methods, and
presented some rcsults. As snch, the book should
be of great value to epidemiologists and to
rheumatologists interested in populations. The report gives too little detnilecl data and interpreta-
tions to be of value
William M . O’Brien, M.D.
BINBy Prof. Dr. Giinter W . KO&ing, director, and Priv.-Doz. Dr. Hans Holzmann,
senior physician, Dermatologic Clinic, Johannes
Gutenberg Uniuersity, Mainz. 155 pages, 9%’’ x
6%” (17 x 24 cm.). 125 illustrations, 14 in color.
Stuttgart, Georg Thieme Verlag, 1967. Price DM
The authors of this monograph have succeeded
in presenting not only a concise and comprehensive review of sclerodenna and related conditions,
but also an up-to-date summary of fundamental
information about connective tissue. The comprehensive nature of this work is indicated by its
25 pages of references from the German, English,
French, and Italian language literature, including
articles from 1967. The clinical section begins
with a discussion of the relationship of scleroderma and various actual and possible clinical
entities. No two authors will agree entirely on
which conditions are relevant, I doubt that necrobiosis lipoidica (p. 17-18) needs to be considered,
while the CRST syndrome should be, but is not.
Next, the clinical aspects of the circumscribed
forms of sclerodenna and the cutaneous manifestations of progressive systemic sclerosis (PSS)
are presented, followed by the dermopatliology
as studied by light and electron microscopy. Involvement of each of the other organs by PSS
is then considered, followed by the relationship
of PSS to neoplasia, to fertility, immunologic and
chemical findings, and genetic considerations. Discussions of experimental lathyrism and of the
effects of therapeutic agents on the metabolism
of mesenchymal tissues are very pertinent, but
might more logically be included in the second
portion of the monograph: “Theoretical Section
(Structure, metabolism and function of connective
tissue) This difficult subject-matter is presented
in outstandingly clear and concise fashion. I know
of nothing similar in a clinical rheumatologic
Illustrations include clinical photographs, roentgenograms, light and electron photomicrographs,
and all are of the highest quality. Surprisingly, neither the roentgenographic or pathologic appearance
of the intestines is shown.
A comparison with the recent American monograph by M. A. Sackner, Sclerodernza, is in order.
In recent years much quantitative pathophysiologic
information has accrued, especially pertaining to
the cardiorespiratory systems. While the pertinent
articles are contained in the bibliography of the
Без категории
Размер файла
114 Кб
art, 1780100609
Пожаловаться на содержимое документа