2005
Fused pyridine derivatives
R 0450
A Two-Step Synthesis of Cytostatically Active Benzo[c]phenanthridine Deriva— With exception of paclitaxel, title compounds (IIIc) and (VI) exhibit higher
23- 142 tives.
cytostatic activities than established cytostatics like cyclophosphamide or fagaronine.
— (CLEMENT*, B.; WEIDE, M.; WOLSCHENDORF, U.; KOCK, I.; Angew.
Chem., Int. Ed. 44 (2005) 4, 635-638; Pharm. Inst., Christian-Albrechts-Univ.,
D-24118 Kiel, Germany; Eng.) — Nuesgen